ADHD Medication Pregnancy: The Good The Bad And The Ugly
ADHD Medication During Pregnancy and Breastfeeding
Women with ADHD must make a difficult decision regarding whether or not to stop taking ADHD medication during pregnancy and breastfeeding. There aren't enough data on how exposure to ADHD for a long time could affect the pregnant fetus.
A recent study published in Molecular Psychiatry shows that children exposed to ADHD medication during the uterus don't develop neurological developmental disorders like hearing loss or impaired vision seizures, febrile seizures, or IQ impairment. The authors acknowledge that more high quality studies are needed.
Risk/Benefit Analysis
Women who are expecting and taking ADHD medication must consider the benefits of taking it against the potential risks to the baby. Physicians don't have the data needed to make unequivocal recommendations but they can provide information on the risks and benefits to aid pregnant women in making informed decisions.
A study published in Molecular Psychiatry found that women who can prescribe adhd medication took ADHD medications during early pregnancy did not face a significantly increased risk of fetal heart malformations or major birth defects that are structural. Researchers used a vast population-based case-control study to evaluate the incidence of major structural birth defects in infants born to mothers who took stimulants during the early stages of pregnancy and those who had not. Clinical geneticists and pediatric cardiologists examined the cases to ensure accurate case classification and to limit the possibility of bias.
However, the researchers' study was not without its flaws. Most important, they were unable to separate the effects of the medication from the effects of the underlying disorder. This makes it difficult for researchers to establish whether the few associations observed between the exposed groups were due to the use of medications or if they were caused by co-morbidities. The researchers did not study long-term outcomes for the offspring.
The study did show that babies whose mothers had taken ADHD medications during pregnancy were at a slightly more risk of being admitted to the neonatal intensive care unit (NICU) than those who were born without any medication or had taken off their medication prior to or during pregnancy. This increase was caused by central nervous system disorders. The increased risk of admission was not influenced by the stimulant medications used during pregnancy.
Women who took stimulant ADHD medications during pregnancy also had a higher chance of having to have a caesarean section or a baby that scored low on the Apgar scale (less than 7). These increases didn't appear to be affected by the kind of medication used during pregnancy.
The research suggests that the risk of a small amount with the use of ADHD medications during the early stages of pregnancy may be offset by the greater benefits for both mother and child of continuing treatment for the woman's condition. Doctors should discuss with their patients about this and, if possible, help them improve coping skills which can lessen the impact of her disorder in her daily life and relationships.
Medication Interactions
Many doctors are faced with the decision of whether to continue treatment or stop during pregnancy as more women are diagnosed with ADHD. Most of the time, these decisions are taken in the absence of any evidence that is clear and definitive regardless, so doctors must weigh what they know about their experiences, the experiences of other doctors, and what the research suggests on the subject as well as their own judgments for each patient.
The issue of possible risks for infants can be particularly tricky. Many studies on this issue are based on observational evidence rather than controlled research and their findings are often contradictory. The majority of studies restrict their analysis to live births, which may underestimate the severity of teratogenic effects that can you get adhd medication without a diagnosis uk lead to terminations or abortions of pregnancy. The study discussed in the journal club addresses these issues by analyzing both the data from deceased and live births.
The conclusion The conclusion: While some studies have shown that there is a positive correlation between ADHD medications Prescribed for adhd and the possibility of certain birth defects, others have not found any evidence of a link, and most studies demonstrate a neutral or slightly negative effect. In the end, a careful risk/benefit assessment must be done in each case.
For women suffering from ADHD, the decision to stop medication is difficult if not impossible. In a recent article in Archives of Women's Mental Health psychologist Jennifer Russell notes that stopping adhd medication weekends adults adhd treatment medication medication during pregnancy can lead to increased depression, feelings of loneliness and family conflict for these patients. A decrease in medication could also affect the ability to safely drive and perform work-related tasks, which are crucial aspects of normal life for those suffering from ADHD.
She suggests women who are unsure about whether to keep or stop taking medication because of their pregnancy, consider educating family members, friends, and coworkers on the condition, its impact on daily functioning, and the advantages of staying on the current treatment plan. Educating them can also help the woman feel supported as she struggles with her decision. It is also worth noting that some medications can pass through the placenta, therefore, if a patient decides to stop her ADHD medication during pregnancy and breastfeeding, she should be aware that traces of the medication could be passed on to the baby.
Risk of Birth Defects
As the use of ADHD medications to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows as do concerns about what impact the drugs could have on fetuses. A study that was published in the journal Molecular Psychiatry adds to the existing knowledge on this subject. Researchers utilized two massive data sets to examine over 4.3 million pregnancies and determine if stimulant medication use increased the risk of birth defects. Although the risk overall is low, the researchers did find that first-trimester exposure to ADHD medications was associated with a slightly higher rate of specific heart defects, such as ventriculo-septal defect (VSD).
The authors of the study could not find any association between early medication usage and other congenital anomalies, like facial deformities or club feet. The results are in line with previous studies which showed a small, but significant increase in cardiac malformations for women who began taking ADHD medication prior to the time of the birth of their child. This risk increased during the latter half of pregnancy, when a lot of women decided to stop taking their medication.
Women who took ADHD medication in the first trimester were more likely need a caesarean, have a low Apgar after birth and have a baby who needed help breathing when they were born. However the researchers of the study were not able to eliminate selection bias by restricting the study to women who didn't have other medical issues that could have contributed to the findings.
The researchers hope their research will aid in the clinical decisions of physicians who treat pregnant women. They recommend that, while a discussion of risks and benefits is important, the decision to stop or continue treatment must be based on each woman's requirements and the severity of her ADHD symptoms.
The authors also advise that while discontinuing the medications is an alternative, it is not an option to consider due to the high rate of depression and other mental health problems among women who are pregnant or who are recently post-partum. Additionally, research suggests that women who stop taking their medications will have a harder time adjusting to a life without them after the baby is born.
Nursing
The responsibilities of a new mother can be overwhelming. Women who suffer from ADHD can face severe challenges when they must manage their symptoms, go to doctor appointments and prepare for the birth of their child and adjust to new routines. Therefore, many women elect to continue taking their ADHD medications throughout the course of pregnancy.
The risk for breastfeeding infant is not too high since the majority of stimulant medication passes through breast milk in low amounts. However, the rate of exposure to medication by the newborn can vary depending on dosage, how often it is administered, and the time of day it is administered. Additionally, different medications enter the infant's system differently through the gastrointestinal tract and breast milk, and the effect of this on a newborn isn't fully known.
Some physicians may discontinue stimulant medication during a woman’s pregnancy due to the absence of research. It's a difficult choice for the mother, who must weigh the advantages of her medication against the risk to the embryo. Until more information is available, doctors should ask all pregnant patients about their history of ADHD and if they are taking or planning to take medication during the perinatal time.
Numerous studies have demonstrated that women can continue taking their ADHD medication in a safe manner during pregnancy and while breast-feeding. In response, a rising number of patients are choosing to do this. They have found after consulting with their doctor that the benefits of continuing their current medication outweigh possible risks.
It is essential for women with ADHD who are thinking of breastfeeding to seek a specialist psychiatrist's guidance prior to becoming pregnant. They should discuss their medication with their physician and discuss the advantages and disadvantages of continuing treatment, including non-pharmacological management strategies. Psychoeducation is also needed to help pregnant women with ADHD recognize the signs and underlying disorder. They should also be informed about treatment options and build coping mechanisms. This should include a multidisciplinary approach with the GP, obstetricians and psychiatry. Pregnancy counseling should consist of a discussion of a treatment plan for the mother and child, monitoring of signs of deterioration, and, if needed, adjustments to the medication regime.